I'm mostly sold. The only downside is that the preformatted text blocks have each line start with a ':'. That makes it terrible for naive copy/paste from the source document...
In Emacs, <s + <TAB> at the beginning of a line starts a source block. The delimiters are quite distracting though. This is an issue I have with markup languages in general, either you use markup very sparingly or the document easily becomes unreadable.
But other than that, it really does look great.