Not the same - sites will then take your not opting out of "legitimate interest" as consent. Not valid under GDPR really, but I'm not interested in giving them any argument to stand on.
* The laws specify that it must be opt-in. If a site doesn't respect this, you can't expect it to respect any of your choices anyway.
* You can now also use uBlock Origin to set cookies and LocalStorage entries automatically. The annoyance lists already set opt-out cookies for sites like Google and Youtube
* Firefox has actually been isolating third-party cookies and other site data (e.g. LocalStorage) for over a year. It's pointless for you to ever be concerned about them.
Client side data is only part of the problem, and it's a common myopic argument to GDPR for opponents of GDPR to say people should just use their browser's cookie controls. Server side fingerprinting is as much as a problem, something the ad industry has adopted since Safari added ITP and are accelerating since Chrome has been making noises about following Safari and Firefox for a few years now. I suspect as soon as Google figures out how to do it without disrupting their own ad business it'll come into effect.
You don't need this. Just go to your uBlock Origin filter lists settings and enable these:
* AdGuard - Annoyances
* uBlock filters – Annoyances