What’s PEM?

PEM is post-exertional malaise, the hallmark symptom of mecfs and some portion of what we call long covid. It's brutal, trying to push through it can lead to permanent worsening of symptom severity.

I’m currently wearing a CGM from Lingo (https://www.hellolingo.com/) which is pretty much the easiest way I’ve found to get my hands on one without a prescription (as I’m not diabetic).

So far it’s shown me that the sluggishness after a carb-heavy meal its heavily correlated with the glucose spike and how good my organism copes with it.

Can’t wait for the day we have our own Fallout style Pip-Boys!

Astro - https://astro.build/

Is probably the fastest thing you can use with extremely sensible defaults and that you can use alongside most web frameworks.

I've been using React for 6 years but this has changed my view of what is possible. You can write React/Vue and have it compiled statically or keep the component's interactivity.

It's the tool I had been looking for for years.

>Leverage Astro's unique zero-JS frontend architecture to unlock higher conversion rates with better SEO.

I don't know Astro, and I'm sure other frameworks write similar stuff on their landing pages, but this state of web design just makes me puke.

Me too. It’s absurd

I was always inclined to think it meant "the way" or "the road".

Thanks for sharing, I always wanted to see what was inside these beautiful properties! (If you go to the lettings section you can actually see individual properties and their HEFTY price)

We just need to see Gattaca to be horrified at the results of such experiment.

I have seen Gattaca and don't find human genetic engineering to be horrific. It's cool and exciting that people will be able to have better children than they would have otherwise.

> I have seen Gattaca and don't find human genetic engineering to be horrific. It's cool and exciting that people will be able to have better children than they would have otherwise.

Did you even pay attention to the movie? The horrific aspect was the human genetic engineering led 1) to the the unengineered to be turned into an underclass that was blatantly and unfairly discriminated against, and 2) that same discrimination would be turned against the engineered if they had an accident that caused them to fall short of the expected perfection.

I have little doubt that the reality of genetic engineering (that was is effective as that depicted) would rhyme with that movie. It's also nearly certain that any such technology would not be distributed in an egalitarian way, so the sentiment should be more like "it's cool and exciting that [well off] people will be able to have [genetically superior] children than [the plebs]."

I understood the intention of the movie, but I'm also in the camp that thinks engineering ourselves is the way forward, and a given. Genetic and silicon advances have a real potential to make us super/transhuman and immortal.

> It's also nearly certain that any such technology would not be distributed in an egalitarian way

This argument could have been made about early computers as well. But time and its economies of scale come into play. We can't limit our species based on shortsighted fairness, there's a longer view to take.

This response would have been perfect if you had signed off with "Sent from my iPhone"

> This response would have been perfect if you had signed off with "Sent from my iPhone"

Because it's a distraction box or so amazing that it shows technology should not be criticized and everyone who does is a hypocrite?

Hrm. So what? How is that different from the uneven distribution of money/wealth/power/medicine/upbringing/private schools/university/"connectedness" today?

This will be just another currency. And there will be some flops, busts, unintended consequences. Just like with anything else.

Ist mir scheissegal!

> Hrm. So what? How is that different from the uneven distribution of money/wealth/power/medicine/upbringing/private schools/university/"connectedness" today?

Vague resemblance does not an equivalency make.

Right now, there may be an unequal distribution of wealth, etc.; but the wealthy by and large aren't actually better models of human. Genetic engineering has the potential to ossify that (both morally via "meritocracy" and physically) with biological superiority. It stops being Homo sapiens vs Homo sapiens, and becomes something more like Homo erectus vs Homo sapiens.

We have underclasses based on genetics now. Let's not pretend mate selection on Earth in 2022 is a meritocracy. It's mostly just racism, a slower form of deliberate genetic engineering of one's offspring.

If anything, this would increase the amount of opportunity in the world, as then your child could have whatever traits you (or your culture) deems superior. It would perhaps eliminate racism by rendering traditional race markers completely obsolete.

> It's cool and exciting that people will be able to have better children than they would have otherwise.

You know, I used to be wary of eugenics, but when you put in that light, yeah, I'm kinda tired of putting up with everyone's crap kids. If you could make them be quiet, sit still, and do as told, that would be a fantastic achievement! Oh, and maybe make them smarter, too. Ever try to actually talk to one (the newer ones are really pretty stupid)?

Genetic engineering of one's own children is not eugenics. It's not even close.

Most of my friends' children are smart. The ones not raised in the USA are generally well-behaved. Your sample size may need to be increased.

People will balk at this, which is funny in contrast to how much human energy is poured into ego, signaling and mate selection as proxies for perpetuating favorable genetics.

Getting a job straight out of a bootcamp is hard. Getting a front-end job out of a bootcamp without knowing the most popular technologies is even harder.

Bootcamp's interest will always be to increase their students odds to be hired rather than foundational knowledge

200% behind you! My point was not to shoot at bootcamps. (Though currently in Europe my friends working in bootcamps have never seen such a fast hire rate).

Bootcamps follow what the market requires. My main point was more about the market we have created for ourselves :).

Well, in their defence, you can't really know how much the uptime is going to be affected by until the incident is resolved. If it was a live counter then you'd see the uptime go up as the month progresses!

Because then the metrics can't be reviewed/vetoed by executives before being published. Optics > accuracy for most organizations, sadly.

Unfortunately true. About a year ago, I had reported a pod-specific issue to Zendesk (I'm fuzzy on the details). They confirmed the issue but also acknowledged that it would not reflect on status.zendesk.com.

I've questioned status pages since.

Just compute live uptime for the portion of the month that has elapsed thus far…

Cross origin browser cache is a no-go for Safari (and hopefully other browsers will follow suit), 3rd party scripts from a CDN are not cached across different domains. The only way to properly cache things longterm is with webpack records, but not many people can bear with the added complexity of maintaining them in their pipelines.